Advanced Turmeric Curcumin Capsules 1 2 3

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The Studies: Does Advanced Curcumin Really Work?

Curcumin for Osteoarthritis of the knee - A Clinical study

A study published in BMC suggests that curcumin, a naturally occurring substance found in a common spice, might help ease osteoarthritis pain. In the study, researchers enrolled 139 people with symptoms of knee osteoarthritis. Their symptoms were at least moderately severe and required treatment with a nonsteroidal anti-inflammatory drug (NSAID). For one month, they were given the NSAID diclofenac (50 mg, twice daily) or curcumin (500 mg, three times daily). 

Here’s what this study found: Both treatments relieved arthritis symptoms and helped to a similar degree: 94% of those taking curcumin and 97% of those taking diclofenac reported at least 50% improvement.

People reported fewer side effects with curcumin. For example, none of the study subjects taking curcumin needed treatment for stomach trouble, but 28% of those taking diclofenac needed treatment.

Those taking curcumin lost, on average, nearly 2% of their body weight in just four weeks — that’s 3.5 pounds for a 175-pound person.


Curcumin for Rheumatoid arthritis - A Clinical study

Curcumin is known to possess potent antiinflammatory and antiarthritic properties. This pilot clinical study evaluated the safety and effectiveness of curcumin alone, and in combination with diclofenac sodium in patients with active rheumatoid arthritis (RA).

Forty-five patients diagnosed with RA were randomized into three groups with patients receiving curcumin (500 mg) and diclofenac sodium (50 mg) alone or their combination.

The primary endpoints were reduction in Disease Activity Score (DAS) 28. The secondary endpoints included American College of Rheumatology (ACR) criteria for reduction in tenderness and swelling of joint scores.

Patients in all three treatment groups showed statistically significant changes in their DAS scores. Interestingly, the curcumin group showed the highest percentage of improvement in overall DAS and ACR scores (ACR 20, 50 and 70) and these scores were significantly better than the patients in the diclofenac sodium group.

More importantly, curcumin treatment was found to be safe and did not relate with any adverse events. Our study provides the first evidence for the safety and superiority of curcumin treatment in patients with active RA, and highlights the need for future large-scale trials to validate these findings in patients with RA and other arthritic conditions.


Curcumin for Cardiovascular disease - A Clinical study

Another common medical condition that can be treated with curcumin is atherosclerosis, which is widely prevalent in the Western society. Although there are numerous explanations for this pattern of atherosclerotic disease, one of the factors that may play a role is the decreased consumption of natural plant-based products such as curcumin in the Western diet.

Curcumin has demonstrated some efficacy in treating hypercholesterolemia.

One small study found that daily administration of 500 mg of curcumin for one week led to a significant 33% decrease in lipid peroxides, a 29% increase in HDL cholesterol, and a 12% decrease in total body cholesterol. 

Another study also had consistent findings, demonstrating that only 10 mg of curcumin administered twice daily lowered serum LDL and increased HDL.29


Curcumin for Anti Inflammation - A Review of Its’ Effects on Human Health

Oxidative stress has been implicated in many chronic diseases, and its pathological processes are closely related to those of inflammation, in that one can be easily induced by another.

In fact, it is known that inflammatory cells liberate a number of reactive species at the site of inflammation leading to oxidative stress, which demonstrates the relationship between oxidative stress and inflammation [28].

In addition, a number of reactive oxygen/nitrogen species can initiate an intracellular signaling cascade that enhances pro-inflammatory gene expression. Inflammation has been identified in the development of many chronic diseases and conditions [10,19,29,30]. These diseases include Alzheimer’s disease (AD), Parkinson’s disease, multiple sclerosis, epilepsy, cerebral injury, cardiovascular disease, metabolic syndrome, cancer, allergy, asthma, bronchitis, colitis, arthritis, renal ischemia, psoriasis, diabetes, obesity, depression, fatigue, and acquired immune deficiency syndromeAIDS [10]. Tumor necrosis factor α (TNF-α) is a major mediator of inflammation in most diseases, and this effect is regulated by the activation of a transcription factor, nuclear factor (NF)-κB. Whereas TNF-α is said to be the most potent NF-κB activator, the expression of TNF-α is also regulated by NF-κB. In addition to TNF-α, NF-κB is also activated by most inflammatory cytokines; gram-negative bacteria; various disease-causing viruses; environmental pollutants; chemical, physical, mechanical, and psychological stress; high glucose; fatty acids; ultraviolet radiation; cigarette smoke; and other disease-causing factors.

Therefore, agents that downregulate NF-κB and NF-κB–regulated gene products have potential efficacy against several of these diseases. Curcumin has been shown to block NF-κB activation increased by several different inflammatory stimuli [10]. 

Curcumin has also been shown to suppress inflammation through many different mechanisms beyond the scope of this review, thereby supporting its mechanism of action as a potential anti-inflammatory agent [10].


Curcumin for Mental Wellbeing - A Clinical study

Curcumin has shown some promise in treating depression. In a controlled trial, 60 people with depression were randomized into three groups (43Trusted Source).

One group took Prozac, another group took 1 gram of curcumin, and the third group took both Prozac and curcumin. After 6 weeks, curcumin had led to improvements similar to those of Prozac.

The group that took both Prozac and curcumin fared best (44Trusted Source). According to this small study, curcumin is as effective as an antidepressant.

Depression is also linked to reduced levels of BDNF and a shrinking hippocampus, a brain area with a role in learning and memory. 

Curcumin can help boost BDNF levels, potentially reversing some of these changes (45). There’s also some evidence that curcumin can boost the brain neurotransmitters serotonin and dopamine (46, 47).


Can you afford to rely on ineffective supplements? 

Stop wasting money and start getting rid of that dreaded pain.

Traditional turmeric supplements contain very low levels of curcuminoids, leaving you out of pocket with little to no results!

Advanced Curcumin contains the highest levels of curcuminoids with carefully balanced ingredients that help you fully absorb it.

It's time to get real results and give your body what it needs!

Still On The Fence? Read The Top 10 Questions Customers Asked Before Ordering The Pretty Smart Food Co® Advanced Curcumin

Can't find your question? 

  • 01903 357062


Is curcumin the same as turmeric?

Put simply - curcumin is the active ingredient found within the turmeric root. It's what gives turmeric its "magic"!

Why do I need curcumin?

As we start to age, joint movement becomes stiffer and less flexible.

The lubricating fluid inside our joints decreases and the cartilage becomes thinner. Ligaments also tend to shorten and we slowly but surely lose our flexibility, which can make our joints feel stiff and sore.

Curcumin is proven to combat inflammation, reduce pain and promote mobility for easy movement

What are the benefits of curcumin?

Our Advanced Curcumin Capsules provides a hyper concentrated form of curcumin which helps reduce aches, pains - and helps improve comfortable movement and flexibility

Curcumin additionally supports brain, heart, and digestive health.

What are the ingredients of your curcumin capsules?

Curcumin Granulated Extract 95% (from Curcuma longa L.), Vitamin C (Ascorbic Acid), Coconut Oil Powder, Ginger Root Powder (10:1 Extract), Quercetin Dihydrate, Boswellia Serrata Powder (10:1 Extract), Natural Rice Extract (NuMag), Aloe Vera Powder (200:1 Extract), Rosemary Leaf Powder (10:1 Extract), Bioperine® (from Piper nigrum L.), Vitamin D3 Vitashine™ (Cholecalciferol from Algae), Vitamin K2 (as Menaquinone-7).

We don't use any artificial fillers, binders, colours, sweeteners, flavours or preservatives in our capsules!

Who are The Pretty Smart Food Co?

Nice to meet you! 😀 

We're a small team based in Worthing (West Sussex, UK) - on a mission to create nutritionally superior & innovative formulas that go above and beyond traditional supplements. 

We proudly manufacture green and clean in our BRC & Good Manufacturing Practice (GMP) Certified factory in The United Kingdom. Full Batch Manufacturing Records mean every individual pack is 100% traceable.

How long before I see results?

When it comes to taking turmeric, it takes a little while for the curcumin to build up in your system. However, once you’ve gone through a loading period, that’s when you will start to notice some of the proposed benefits.

Depending on your body mass and condition, it will usually take around 4-8 weeks for you to start noticing improvements to your body and mind.

Is this a one-time order or will you put me on a subscription?

This is a one time, one-off order. We obviously hope you love the product and come back to us when you want to order some more. We certainly aren’t like other supplement companies who often put people on to a subscription without making it obvious to them. You will only receive what you intentionally ordered, and nothing extra. 

However, if you would prefer to be on a subscription (so you don’t need to remember to reorder each month) then just get in touch and we can help set that up for you.

Is this product safe to take?

We put ourselves in your shoes and asked: if we were buying supplements, what would we want to know? That brought us to three very important questions we wanted to answer: 

1. Is my product clean? 

2. Is my product what it says it is? 

3. If so, how do I really know those two things? 

This is our answer: Comprehensive testing by accredited laboratories that follow quality standards set forth by the most prestigious national and international organizations. 

We test every product batch for: 

1. Ingredient Potency 

2. Heavy Metal Content 

3. Microbial Contaminants 

4. Pathogens

Can I take this product alongside medication?

Please consult your healthcare provider before taking any supplements if you are taking medication.

Can I take this product if I am pregnant?

Please consult your healthcare provider before taking while pregnant or nursing.

How quickly will I receive my product?

We ship all UK orders out using Royal Mail Tracked, and a shipment tracking number will be sent to you upon dispatch. UK orders normally take about 1-2 days to arrive. International EU orders typically take between 3-5 working days to arrive.

Do we ship to the EU and beyond?

We certainly do! Although we are based in the United Kingdom, we also ship to the EU and most countries worldwide. Hurray! 🎉

Try advanced curcumin today, and start feeling great!

It's zero-risk with our 30 day satisfaction guarantee.

Contact us

  • The Pretty Smart Food Co Ltd, Unit 2, Ham Bridge Trading Estate, Willowbrook Rd, Worthing BN14 8NA, United Kingdom


  • 01903 357062